Monograph: Azithromycin

Azithromycin

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Full Title

Azithromycin

Generic Name

Azithromycin; Azithromycin Dihydrate

Chemical Name

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INV Number

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Classification

CAS Number

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Introduction

Introduction

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Uses

Uses

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Acute Otitis Media

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Pharyngitis and Tonsillitis

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GI Infections

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Campylobacter Infections

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Cryptosporidiosis

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Escherichia coli Infections

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Shigella Infections

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Travelers’ Diarrhea

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Respiratory Tract Infections

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Acute Sinusitis

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Acute Bacterial Exacerbations of Chronic Obstructive Pulmonary Disease

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Community-acquired Pneumonia

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Skin and Skin Structure Infections

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Babesiosis

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Bartonella Infections

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Chancroid

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Patient Follow-up and Management of Sexual Partners

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Chlamydial Infections

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Urogenital Chlamydial Infections

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Urogenital Chlamydial Infection in Adults and Adolescents

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Urogenital Chlamydial Infection in Infants and Children

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Presumptive Treatment of Chlamydial Infection in Patients with Gonorrhea

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Lymphogranuloma Venereum

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Chlamydial Pneumonia in Infants

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Trachoma and Other Ocular Chlamydial Infections

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Other Chlamydial Infections

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Cholera

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Gonorrhea and Associated Infections

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Granuloma Inguinale (Donovanosis)

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Helicobacter pylori Infection and Duodenal Ulcer Disease

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Legionella Infections

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Leptospirosis

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Malaria

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Mycobacterium avium Complex (MAC) Infections

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Primary Prevention of Disseminated MAC Infection

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Treatment and Prevention of Recurrence of Disseminated MAC Infection

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Treatment of Pulmonary MAC Infections in HIV-negative Adults

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Mycobacterium abscessus, M. kansasii, and M. marinum Infections

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Neisseria meningitidis Infections

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Nongonococcal Urethritis

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Pelvic Inflammatory Disease

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Pertussis

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Treatment

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Prevention

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Scrub Typhus

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Spirochetal Infections

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Lyme Disease

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Syphilis

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Toxoplasmosis

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Typhoid Fever and Other Salmonella Infections

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Prevention of Bacterial Endocarditis

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Prophylaxis in Sexual Assault Victims

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Dosage and Administration

Dosage and Administration

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Reconstitution and Administration

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Oral Administration

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Reconstitution

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IV Infusion

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Reconstitution and Dilution

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Rate of Administration

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Dosage

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Adult Dosage

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Pharyngitis and Tonsillitis

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Acute Sinusitis

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Acute Exacerbations of Chronic Bronchitis

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Community-acquired Pneumonia

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Skin and Skin Structure Infections

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Babesiosis

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Bartonella Infections

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Campylobacter Infections

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Chancroid

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Chlamydial Infections

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Cholera

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Cryptosporidiosis

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Gonorrhea and Associated Infections

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Granuloma Inguinale (Donovanosis)

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Legionella Infections

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Leptospirosis

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Lyme Disease

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Lymphogranuloma Venereum

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Mycobacterium avium Complex (MAC) Infections (Primary Prophylaxis of Disseminated Infection)

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Mycobacterium avium Complex (MAC) Infections (Treatment and Prevention of Recurrence of Disseminated Infection)

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Mycobacterium avium Complex (MAC) Infections (Treatment of Pulmonary Infections)

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Mycobacterium abscessus Infections

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Neisseria meningitidis Infections

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Nongonococcal Urethritis

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Pelvic Inflammatory Disease

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Pertussis

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Scrub Typhus

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Syphilis

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Shigella Infections

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Toxoplasmosis

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Travelers’ Diarrhea

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Typhoid Fever and Other Salmonella Infections

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Prevention of Bacterial Endocarditis

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Prophylaxis in Sexual Assault Victims

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Pediatric Dosage

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Acute Otitis Media

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Pharyngitis and Tonsillitis

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Acute Sinusitis

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Community-acquired Pneumonia

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Babesiosis

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Bartonella Infections

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Chancroid

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Chlamydial Infections

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Cryptosporidiosis

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Escherichia coli Infections

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Legionella Infections

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Leptospirosis

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Lyme Disease

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Mycobacterium avium Complex (MAC) Infections (Primary Prophylaxis of Disseminated Infection)

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Mycobacterium avium Complex (MAC) Infections (Treatment and Prevention of Recurrence of Disseminated Infection)

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Pertussis

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Shigella Infections

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Travelers’ Diarrhea

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Typhoid Fever and Other Salmonella Infections

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Prevention of Bacterial Endocarditis

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Dosage in Renal and Hepatic Impairment

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Cautions

Cautions

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GI Effects

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Dermatologic and Sensitivity Reactions

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Local Reactions

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Hepatic Effects

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Renal and Genitourinary Effects

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Cardiovascular Effects

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Nervous System Effects

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Hematologic Effects

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Otic Effects

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Other Adverse Effects

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Effects on Phospholipids

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Precautions and Contraindications

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Pediatric Precautions

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Geriatric Precautions

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Mutagenicity and Carcinogenicity

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Pregnancy, Fertility, and Lactation

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Pregnancy

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Fertility

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Lactation

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Drug Interactions

Drug Interactions

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Drugs Affecting or Metabolized by Hepatic Microsomal Enzymes

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Albendazole

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Antacids

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Antilipemic Agents

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Antimalarial Agents

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Chloroquine

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Quinine

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Antiretroviral Agents

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HIV Protease Inhibitors

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Atazanavir

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Indinavir

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Lopinavir

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Nelfinavir

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Nonnucleoside Reverse Transcriptase Inhibitors

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Efavirenz

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Nucleoside Reverse Transcriptase Inhibitors

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Didanosine

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Zidovudine

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Benzodiazepines

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Carbamazepine

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Cetirizine

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Cimetidine

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Co-trimoxazole

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Cyclosporine

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Digoxin

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Ergot Alkaloids

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Fluconazole

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Ivermectin

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Phenytoin

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Pimozide

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Rifabutin

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Sildenafil

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Theophylline

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Warfarin

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Acute Toxicity

Acute Toxicity

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Pharmacokinetics

Pharmacokinetics

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Absorption

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Food

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Distribution

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Elimination

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Chemistry and Stability

Chemistry and Stability

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Chemistry

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Stability

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Spectrum Section

Spectrum

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In Vitro Susceptibility Testing

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Disk Susceptibility Tests

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Dilution Susceptibility Tests

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Gram-positive Aerobic Bacteria

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Gram-negative Aerobic Bacteria

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Mycobacteria

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Anaerobic Bacteria

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Chlamydiae

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Mycoplasma

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Spirochetes

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Other Organisms

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Resistance Section

Resistance

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Resistance in Gram-positive Bacteria

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Resistance in Neisseria and Treponema

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Resistance in Mycobacteria

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Cross-resistance

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Mechanism of Action

Mechanism of Action

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Preparations

Preparations

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Azithromycin Dihydrate

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References

References

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Copyright

AHFS® Drug Information. © Copyright, 1959-2019, Selected Revisions August 7, 2018. American Society of Health-System Pharmacists, Inc., 4500 East-West Highway, Suite 900, Bethesda, Maryland 20814.

† Use is not currently included in the labeling approved by the US Food and Drug Administration.

Quelle

AHFS Drug Information