Monograph: Foscarnet Sodium

Foscarnet Sodium

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Full Title

Foscarnet Sodium

Generic Name

Foscarnet Sodium

Chemical Name

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INV Number

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Synonym

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Classification

CAS Number

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Introduction

Introduction

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Description

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Spectrum

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Resistance

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Uses

Uses

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Treatment of Cytomegalovirus Infection and Disease

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Cytomegalovirus Retinitis

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Clinical Experience

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Extraocular Cytomegalovirus Infections

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Prevention of Cytomegalovirus Infection and Disease

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Mucocutaneous Herpes Simplex Virus Infections

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Clinical Experience

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Varicella-Zoster Virus Infections

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Dosage and Administration

Dosage and Administration

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General

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Hydration

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Administration

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IV Infusion

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Dilution

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Rate of Administration

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Dosage

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Adult Dosage

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Cytomegalovirus Retinitis

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Cytomegalovirus Esophagitis or Colitis

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Cytomegalovirus Pneumonitis

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Cytomegalovirus Neurologic Disease

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Mucocutaneous Herpes Simplex Virus Infections

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Varicella-Zoster Virus Infections

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Pediatric Dosage

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Cytomegalovirus Retinitis

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Disseminated Cytomegalovirus Infections

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Mucocutaneous Herpes Simplex Virus Infections

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Varicella-Zoster Virus Infections

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Special Populations

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Hepatic Impairment

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Renal Impairment

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Table 1. Recommended Foscarnet Sodium Dosage for Initial Treatment (Induction Therapy) of CMV Retinitis or HSV Infections in Adults Based on Patient’s Creatinine Clearance.1

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Table 2. Recommended Foscarnet Sodium Dosage for Maintenance Therapy of CMV Retinitis in Adults Based on Patient’s Creatinine Clearance.1

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Geriatric Patients

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Cautions

Cautions

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Contraindications

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Warnings/Precautions

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Warnings

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Renal Effects

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Electrolyte and Metabolic Effects

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Nervous System Effects

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Cardiovascular Effects

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Selection and Use of Antivirals

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Sensitivity Reactions

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Hypersensitivity Reactions

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Other Warnings and Precautions

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Administration Precautions

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Genitourinary Effects

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Hematologic Effects

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Sodium Content

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Carcinogenic and Mutagenic Potential

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Effects on Fertility

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Specific Populations

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Pregnancy

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Lactation

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Pediatric Use

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Geriatric Use

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Renal Impairment

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Common Adverse Effects

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Drug Interactions

Drug Interactions

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Drugs Affecting Calcium

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Drugs That Prolong QT Interval

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Nephrotoxic Drugs

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Antiretroviral Agents

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Didanosine and Zidovudine

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Ritonavir

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Antivirals

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Acyclovir

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Cidofovir

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Ganciclovir

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Letermovir

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Diuretics

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Pentamidine

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Probenecid

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Advice to Patients

Advice to Patients

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Preparations

Preparations

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Foscarnet Sodium

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Common general statement Elements

Additional Information

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References

References

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Copyright

AHFS® Drug Information. © Copyright, 1959-2019, Selected Revisions August 19, 2019. American Society of Health-System Pharmacists, Inc., 4500 East-West Highway, Suite 900, Bethesda, Maryland 20814.

† Use is not currently included in the labeling approved by the US Food and Drug Administration.

Quelle

AHFS Drug Information