Monograph: levoFLOXacin

levoFLOXacin

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Full Title

levoFLOXacin

Generic Name

levoFLOXacin

Chemical Name

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INV Number

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Synonym

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Classification

CAS Number

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Introduction

Introduction

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Description

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Spectrum

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Resistance

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Uses

Uses

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Respiratory Tract Infections

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Acute Sinusitis

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Clinical Experience

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Acute Exacerbations of Chronic Bronchitis

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Clinical Experience

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Community-acquired Pneumonia

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Clinical Experience

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Nosocomial Pneumonia

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Clinical Experience

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Skin and Skin Structure Infections

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Clinical Experience

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Urinary Tract Infections and Prostatitis

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Uncomplicated Urinary Tract Infections

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Complicated Urinary Tract Infections

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Prostatitis

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Endocarditis

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GI Infections

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Campylobacter Infections

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Salmonella Gastroenteritis

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Shigella Infections

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Travelers' Diarrhea

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Treatment

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Prophylaxis

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Helicobacter pylori Infection

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Anthrax

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Chlamydial Infections

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Gonorrhea and Associated Infections

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Mycobacterial Infections

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Treatment of Active Tuberculosis

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Other Mycobacterial Infections

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Nongonococcal Urethritis

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Pelvic Inflammatory Disease

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Plague

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Ophthalmic Infections

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Dosage and Administration

Dosage and Administration

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Administration

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Oral Administration

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IV Infusion

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Rate of Administration

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Dosage

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Pediatric Dosage

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Postexposure Prophylaxis of Anthrax

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Treatment of Uncomplicated Cutaneous Anthrax

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Treatment of Systemic Anthrax

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Plague

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Adult Dosage

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Acute Sinusitis

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Acute Exacerbations of Chronic Bronchitis

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Community-acquired Pneumonia

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Nosocomial Pneumonia

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Skin and Skin Structure Infections

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Urinary Tract Infections and Prostatitis

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Campylobacter Infections

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Salmonella Gastroenteritis

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Shigella Infections

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Travelers' Diarrhea

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Helicobacter pylori Infection

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Postexposure Prophylaxis of Anthrax

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Treatment of Uncomplicated Cutaneous Anthrax

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Treatment of Systemic Anthrax

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Chlamydial Infections

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Epididymitis

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Treatment of Active Tuberculosis

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Treatment of Other Mycobacterial Infections

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Nongonococcal Urethritis

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Pelvic Inflammatory Disease

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Plague

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Special Populations

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Hepatic Impairment

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Renal Impairment

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Table 1. Levofloxacin Dosage for Adults with Renal Impairment128

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Geriatric Patients

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Cautions

Cautions

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Contraindications

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Warnings/Precautions

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Warnings

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Disabling and Potentially Irreversible Serious Adverse Reactions

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Tendinitis and Tendon Rupture

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Peripheral Neuropathy

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CNS Effects

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Exacerbation of Myasthenia Gravis

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Sensitivity Reactions

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Hypersensitivity Reactions

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Photosensitivity Reactions

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Other Warnings/Precautions

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Hepatotoxicity

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Prolongation of QT Interval

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Risk of Aortic Aneurysm and Dissection

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Hypoglycemia or Hyperglycemia

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Musculoskeletal Disorders

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C. difficile-associated Diarrhea and Colitis

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Selection and Use of Anti-infectives

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Specific Populations

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Pregnancy

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Lactation

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Pediatric Use

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Geriatric Use

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Hepatic Impairment

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Renal Impairment

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Common Adverse Effects

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Drug Interactions

Drug Interactions

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Drugs That Prolong QT Interval

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Antacids

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Antiarrhythmic Agents

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Antidepressants

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Antidiabetic Agents

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Cimetidine

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Corticosteroids

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Cyclosporine and Tacrolimus

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Didanosine

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Digoxin

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Iron, Multivitamins, and Mineral Supplements

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Nonsteroidal Anti-inflammatory Agents

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Probenecid

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Sucralfate

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Theophylline

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Warfarin

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Pharmacokinetics

Pharmacokinetics

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Absorption

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Bioavailability

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Food

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Distribution

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Extent

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Plasma Protein Binding

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Elimination

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Metabolism

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Elimination Route

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Half-life

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Special Populations

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Advice to Patients

Advice to Patients

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Preparations

Preparations

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levoFLOXacin

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levoFLOXacin in Dextrose

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Common general statement Elements

Additional Information

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References

References

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Copyright

AHFS® Drug Information. © Copyright, 1959-2019, Selected Revisions August 26, 2019. American Society of Health-System Pharmacists, Inc., 4500 East-West Highway, Suite 900, Bethesda, Maryland 20814.

† Use is not currently included in the labeling approved by the US Food and Drug Administration.

Quelle

AHFS Drug Information