Monograph: Polatuzumab Vedotin-piiq

Polatuzumab Vedotin-piiq

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Full Title

Polatuzumab Vedotin-piiq

Generic Name

Polatuzumab Vedotin

Chemical Name

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INV Number

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Classification

CAS Number

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Introduction

Introduction

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Description

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Uses

Uses

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Non-Hodgkin Lymphoma

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Diffuse Large B-cell Lymphoma

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Dosage and Administration

Dosage and Administration

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General

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Reconstitution and Administration

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Table 1: Recommended Storage Conditions for Diluted Polatuzumab Vedotin-piiq Solutions

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Dosage

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Non-Hodgkin Lymphoma

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Diffuse Large B-cell Lymphoma

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Dosage Modification for Toxicity

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Peripheral Neuropathy

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Infusion-related Reactions

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Hematologic Toxicity

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Special Populations

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Cautions

Cautions

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Contraindications

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Warnings/Precautions

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Peripheral Neuropathy

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Infusion-related Effects

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Hematologic Effects

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Infectious Complications

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Progressive Multifocal Leukoencephalopathy

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Tumor Lysis Syndrome

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Hepatotoxicity

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Fetal/Neonatal Morbidity and Mortality.

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Immunogenicity

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Impairment of Fertility

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Specific Populations

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Pregnancy

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Lactation

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Pediatric Use

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Geriatric Use

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Hepatic Impairment

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Renal Impairment

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Common Adverse Effects

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Drug Interactions

Drug Interactions

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Drugs Affecting Hepatic Microsomal Enzymes

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CYP3A Inhibitors

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CYP3A Inducers

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Drugs Metabolized by Hepatic Microsomal Enzymes

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Substrates of CYP3A Isoenzymes

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Bendamustine

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Rituximab

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Advice to Patients

Advice to Patients

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Preparations

Preparations

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Polatuzumab Vedotin-piiq

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Common general statement Elements

Additional Information

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References

References

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Copyright

AHFS® Drug Information. © Copyright, 1959-2020, Selected Revisions September 28, 2020. American Society of Health-System Pharmacists, Inc., 4500 East-West Highway, Suite 900, Bethesda, Maryland 20814.

Quelle

AHFS Drug Information