Monograph: Opiate Agonists General Statement

Opiate Agonists General Statement

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Full Title

Opiate Agonists General Statement

Classification

Introduction

Introduction

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Uses

Uses

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Pain

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Chronic Pain

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Chronic Noncancer Pain

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Chronic Cancer Pain

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Acute Pain

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Acute Coronary Syndromes

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Pain in Critically Ill Patients

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Vascular Headaches

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Delirium

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Acute Pulmonary Edema

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Preoperative Sedation

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Cough

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Detoxification and Maintenance of Opiate Dependence

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Neonatal Opiate Withdrawal

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Dosage and Administration

Dosage and Administration

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Administration

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Dosage

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Table 1. Comparative Opiate Agonist Dosage with Oral or Parenteral Administration

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Extended-release and Long-acting Formulations for the Management of Chronic Pain

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Cautions

Cautions

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Respiratory Depression

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Nervous System Effects

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GI Effects

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Cardiovascular Effects

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Genitourinary and Endocrine Effects

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Cholinergic Effects

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Other Adverse Effects

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Precautions and Contraindications

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Pediatric Precautions

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Geriatric Precautions

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Pregnancy and Lactation

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Pregnancy

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Lactation

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Drug Interactions

Drug Interactions

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Benzodiazepines and Other CNS Depressants

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Antidepressants

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Drugs Associated with Serotonin Syndrome

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Opiate Antagonists and Opiate Partial Agonists

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Drugs Affecting Hepatic Microsomal Enzymes

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Drugs Affecting the P-glycoprotein Transport System

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Drugs that Prolong QT Interval

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Anticholinergic Agents

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Neuromuscular Blocking Agents

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Amphetamines

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Diuretics

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Chronical Toxicity

Chronic Toxicity

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Acute Toxicity

Acute Toxicity

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Manifestation

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Treatment

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Pharmacology

Pharmacology

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Nervous System Effects

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Ocular Effects

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GI Effects

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Genitourinary Effects

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Cardiovascular Effects

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Effects on Histamine

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Endocrine Effects

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Other Effects

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Pharmacokinetics

Pharmacokinetics

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Absorption and Distribution

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Elimination

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Pharmacogenomics

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Chemistry Section

Chemistry

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Phenanthrene Derivatives

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Phenylpiperidine Derivatives

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Diphenylheptane Derivatives

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Common monograph Elements

Related Monographs

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References

References

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Copyright

AHFS® Drug Information. © Copyright, 1959-2020, Selected Revisions September 21, 2020. American Society of Health-System Pharmacists, Inc., 4500 East-West Highway, Suite 900, Bethesda, Maryland 20814.

† Use is not currently included in the labeling approved by the US Food and Drug Administration.

Quelle

AHFS Drug Information