Monograph: Ziprasidone

Ziprasidone

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Full Title

Ziprasidone

Generic Name

Ziprasidone Hydrochloride; Ziprasidone; Ziprasidone Mesylate

Chemical Name

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INV Number

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Synonym

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Classification

CAS Number

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Introduction

Introduction

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Description

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Uses

Uses

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Psychotic Disorders

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Schizophrenia

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Bipolar Disorder

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Dosage and Administration

Dosage and Administration

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Administration

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Dosage

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Schizophrenia

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Oral Dosage

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IM Dosage

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Bipolar Disorder

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Oral Dosage

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Special Populations

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Cautions

Cautions

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Contraindications

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Warnings/Precautions

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Warnings

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Increased Mortality in Geriatric Patients with Dementia-related Psychosis

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Other Warnings and Precautions

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Prolongation of QT Interval and Risk of Sudden Death

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Neuroleptic Malignant Syndrome

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Severe Cutaneous Adverse Reactions

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Tardive Dyskinesia

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Metabolic Changes

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Hyperglycemia and Diabetes Mellitus

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Dyslipidemia

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Weight Gain

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Rash

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Orthostatic Hypotension

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Leukopenia, Neutropenia, and Agranulocytosis

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Seizures

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Dysphagia

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Hyperprolactinemia

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Cognitive and Motor Impairment

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Priapism

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Body Temperature Regulation

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Suicide

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Concomitant Illnesses

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Specific Populations

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Pregnancy

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Lactation

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Pediatric Use

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Geriatric Use

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Hepatic Impairment

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Renal Impairment

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Common Adverse Effects

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Drug Interactions

Drug Interactions

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Drugs Affecting Hepatic Microsomal Enzymes

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Drugs Metabolized by Hepatic Microsomal Enzymes

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Drugs that Prolong QT Interval

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Protein-bound Drugs

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Antacids

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Anticholinergic Agents

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Hypotensive Agents

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CNS Agents or Alcohol

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Benztropine

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Carbamazepine

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Cimetidine

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Dextromethorphan

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Diuretics

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Ketoconazole and Other CYP3A4 Inhibitors

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Levodopa and Dopamine Agonists

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Lithium

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Lorazepam

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Oral Contraceptives

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Propranolol

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Valproate

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Warfarin

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Smoking

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Advice to Patients

Advice to Patients

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Preparations

Preparations

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Ziprasidone Hydrochloride

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Ziprasidone Mesylate

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Common general statement Elements

Additional Information

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References

References

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Copyright

AHFS® Drug Information. © Copyright, 1959-2020, Selected Revisions January 1, 2016. American Society of Health-System Pharmacists, Inc., 4500 East-West Highway, Suite 900, Bethesda, Maryland 20814.

Quelle

AHFS Drug Information