Monograph: Milnacipran Hydrochloride

Milnacipran Hydrochloride

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Full Title

Milnacipran Hydrochloride

Generic Name

Milnacipran Hydrochloride

Chemical Name

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INV Number

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Synonym

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Classification

CAS Number

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Introduction

Introduction

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Description

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Uses

Uses

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Fibromyalgia

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Major Depressive Disorder

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Dosage and Administration

Dosage and Administration

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Administration

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Dosage

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Fibromyalgia

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Discontinuance of Therapy

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Special Populations

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Cautions

Cautions

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Contraindications

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Warnings/Precautions

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Warnings

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Worsening of Depression and Suicidality Risk

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Other Warnings and Precautions

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Serotonin Syndrome

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Elevated Blood Pressure

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Elevated Heart Rate

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Seizures

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Hepatic Effects

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Withdrawal of Therapy

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Hyponatremia/Syndrome of Inappropriate Antidiuretic Hormone Secretion

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Abnormal Bleeding

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Activation of Mania/Hypomania

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Patients with History of Dysuria

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Angle-closure Glaucoma

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Concomitant Use with Alcohol

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Specific Populations

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Pregnancy

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Lactation

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Pediatric Use

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Geriatric Use

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Hepatic Impairment

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Renal Impairment

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Common Adverse Effects

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Drug Interactions

Drug Interactions

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Drugs Metabolized by Hepatic Microsomal Enzymes

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Drugs Affecting Hepatic Microsomal Enzymes

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Drugs Affecting Hemostasis

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CNS-active Drugs

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Monoamine Oxidase Inhibitors

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Serotonergic Drugs

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Clomipramine

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Fluoxetine

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Lithium

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Drugs that Increase Blood Pressure and Heart Rate

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Alcohol

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Carbamazepine

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Clonidine

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Digoxin

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Diuretics

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Epinephrine and Norepinephrine

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Linezolid

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Lorazepam

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Methylene Blue

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Pregabalin

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Advice to Patients

Advice to Patients

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Preparations

Preparations

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Milnacipran Hydrochloride

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Common general statement Elements

Additional Information

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References

References

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Copyright

AHFS® Drug Information. © Copyright, 1959-2020, Selected Revisions June 1, 2015. American Society of Health-System Pharmacists, Inc., 4500 East-West Highway, Suite 900, Bethesda, Maryland 20814.

† Use is not currently included in the labeling approved by the US Food and Drug Administration.

Quelle

AHFS Drug Information