Monograph: AbobotulinumtoxinA

AbobotulinumtoxinA

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Full Title

AbobotulinumtoxinA

Generic Name

AbobotulinumtoxinA

Chemical Name

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INV Number

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Synonym

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Classification

CAS Number

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Introduction

Introduction

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Description

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Uses

Uses

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Cervical Dystonia

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Cosmesis of Glabellar Facial Lines

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Spasticity

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Upper Limb Spasticity in Adults

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Lower Limb Spasticity in Adults

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Lower Limb Spasticity in Pediatric Patients

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Blepharospasm

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Dosage and Administration

Dosage and Administration

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Reconstitution and Administration

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Dosage

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Cervical Dystonia

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Cosmesis of Glabellar Facial Lines

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Spasticity

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Upper Limb Spasticity in Adults

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Table 1: Dosing of AbobotulinumtoxinA for Upper Limb Spasticity in Adults

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Lower Limb Spasticity in Adults

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Table 2: Dosing of AbobotulinumtoxinA for Lower Limb Spasticity in Adults

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Lower Limb Spasticity in Pediatric Patients

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Table 3. Dosing of AbobotulinumtoxinA for Lower Limb Spasticity in Pediatric Patients

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Cautions

Cautions

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Contraindications

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Warnings/Precautions

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Warnings

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Distant Spread of Toxin Effects

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Sensitivity Reactions

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Hypersensitivity

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Intradermal Sensitivity

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Other Warnings and Precautions

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Lack of Interchangeability Among Botulinum Toxin Preparations

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Dysphagia/Breathing Difficulties

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Administration Precautions in Individuals with Glabellar Facial Lines

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Preexisting Neuromuscular Disorders

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Risk of Viral Transmission

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Immunogenicity

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Reporting Adverse Effects or Overdosage

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Specific Populations

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Pregnancy

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Lactation

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Pediatric Use

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Geriatric Use

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Response in Various Ethnic Groups

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Common Adverse Effects

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Drug Interactions

Drug Interactions

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Anticholinergic Drugs

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Drugs Interfering with Neuromuscular Transmission

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Concurrent or Sequential Botulinum Toxin Treatment

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Advice to Patients

Advice to Patients

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Preparations

Preparations

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AbobotulinumtoxinA

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Common general statement Elements

Additional Information

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References

References

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Copyright

AHFS® Drug Information. © Copyright, 1959-2020, Selected Revisions March 25, 2019. American Society of Health-System Pharmacists, Inc., 4500 East-West Highway, Suite 900, Bethesda, Maryland 20814.

† Use is not currently included in the labeling approved by the US Food and Drug Administration.

Quelle

AHFS Drug Information