Monograph: Acalabrutinib
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Acalabrutinib
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Full Title
Acalabrutinib
Generic Name
Acalabrutinib
Chemical Name
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INV Number
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Classification
CAS Number
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Introduction
Introduction
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...Description
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...Uses
Uses
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Mantle Cell Lymphoma
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...Dosage and Administration
Dosage and Administration
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General
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Restricted Distribution
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Administration
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Concomitant Use with Drugs Affecting Gastric Acidity
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Dosage
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Mantle Cell Lymphoma
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Dosage Modification for Toxicity
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Table 1: Recommended Dosage Modifications for Acalabrutinib Toxicity
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Concomitant Use with Drugs Affecting Hepatic Microsomal Enzymes
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Special Populations
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...Cautions
Cautions
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Contraindications
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Warnings/Precautions
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Hemorrhage
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Infectious Complications
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Myelosuppression
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Development of Second Primary Malignancy
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Atrial Fibrillation and Flutter
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Fetal/Neonatal Morbidity and Mortality
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Specific Populations
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Pregnancy
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Lactation
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Pediatric Use
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Geriatric Use
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Hepatic Impairment
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Renal Impairment
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Common Adverse Effects
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...Drug Interactions
Drug Interactions
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Drugs Affecting Hepatic Microsomal Enzymes
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Inhibitors of CYP3A
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Inducers of CYP3A
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Drugs Metabolized by Hepatic Microsomal Enzymes
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Substrates of Breast Cancer Resistance Protein
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Drugs Affecting Gastric Acidity
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Proton-pump Inhibitors
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Histamine H2-receptor Antagonists
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Antacids
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Anticoagulants and Antiplatelet Agents
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...Advice to Patients
Advice to Patients
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...Preparations
Preparations
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Acalabrutinib
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...Common general statement Elements
Additional Information
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...References
References
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...Copyright
AHFS® Drug Information. © Copyright, 1959-2020, Selected Revisions October 8, 2018. American Society of Health-System Pharmacists, Inc., 4500 East-West Highway, Suite 900, Bethesda, Maryland 20814.
Quelle
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