Monograph: Atovaquone

Atovaquone

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Full Title

Atovaquone

Generic Name

Atovaquone

Chemical Name

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INV Number

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Synonym

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Classification

CAS Number

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Introduction

Introduction

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Uses

Uses

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Pneumocystis jirovecii Pneumonia

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Treatment of Pneumocystis jirovecii Pneumonia

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Prevention of Pneumocystis jirovecii Infections

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Prevention of Initial Episode (Primary Prophylaxis)

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Prevention of Recurrence (Secondary Prophylaxis)

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Primary and Secondary Prophylaxis in Children

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Toxoplasmosis

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Treatment of Toxoplasmosis

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Prevention of Toxoplasmosis

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Prevention of Initial Episode (Primary Prophylaxis)

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Prevention of Recurrence (Secondary Prophylaxis)

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Primary and Secondary Prophylaxis in Children

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Babesiosis

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Malaria

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Dosage and Administration

Dosage and Administration

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Administration

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Dosage

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Pneumocystis jirovecii Pneumonia

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Treatment of Pneumocystis jirovecii Pneumonia

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Prevention of Initial Episode (Primary Prophylaxis)

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Prevention of Recurrence (Secondary Prophylaxis)

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Toxoplasmosis

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Treatment of Toxoplasmosis

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Prevention of Initial Episode (Primary Prophylaxis)

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Prevention of Recurrence (Secondary Prophylaxis)

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Babesiosis

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Dosage in Renal and Hepatic Impairment

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Cautions

Cautions

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Dermatologic and Sensitivity Reactions

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GI Effects

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Nervous System Effects

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Hematologic Effects

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Hepatic Effects

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Renal and Electrolyte Effects

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Metabolic Effects

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Other Adverse Effects

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Precautions and Contraindications

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Pediatric Precautions

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Geriatric Precautions

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Mutagenicity and Carcinogenicity

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Pregnancy, Fertility, and Lactation

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Pregnancy

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Fertility

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Lactation

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Drug Interactions

Drug Interactions

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Protein-bound Drugs

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Antimycobacterial Agents

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Co-trimoxazole

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Metoclopramide

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Phenytoin

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Tetracycline

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Zidovudine

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Pharmacokinetics

Pharmacokinetics

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Absorption

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Distribution

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Elimination

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Chemistry and Stability

Chemistry and Stability

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Chemistry

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Stability

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Spectrum Section

Spectrum

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Resistance Section

Resistance

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Mechanism of Action

Mechanism of Action

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Preparations

Preparations

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Atovaquone

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References

References

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Copyright

AHFS® Drug Information. © Copyright, 1959-2020, Selected Revisions August 29, 2014. American Society of Health-System Pharmacists, Inc., 4500 East-West Highway, Suite 900, Bethesda, Maryland 20814.

† Use is not currently included in the labeling approved by the US Food and Drug Administration.

Quelle

AHFS Drug Information