Monograph: Abacavir Sulfate

Abacavir Sulfate

Die Inhalte stehen nur registrierten Benutzern zur Verfügung.

Sie sind zum ersten mal hier und möchten die Datenbank 10-Tage kostenlos testen, dann registrieren Sie sich einmalig. Nach der Registrierung melden Sie sich mit Ihrem Benutzernamen und Passwort an.

Sie sind bereits bei DrugBase registriert und möchten diese Datenbank 10-Tage kostenlos und unverbindlich testen? Dann melden Sie sich mit Ihren Zugangsdaten an und wählen Sie anschließend die Datenbank, die Sie testen möchten.

Full Title

Abacavir Sulfate

Generic Name

Abacavir Sulfate; Abacavir Sulfate and Lamivudine; Abacavir Sulfate, Dolutegravir, and Lamivudine; Abacavir Sulfate, Lamivudine, and Zidovudine

Chemical Name

...

INV Number

...

Classification

CAS Number

...

Introduction

Introduction

...

...

...

Uses

Uses

...

Treatment of HIV Infection

...

Antiretroviral-naive Adults and Adolescents

...

Dual NRTI Options

...

All-NRTI Regimens

...

Dolutegravir, Abacavir, and Lamivudine

...

Efavirenz, Abacavir, and Lamivudine

...

PI-based Regimens

...

Antiretroviral-experienced Adults and Adolescents

...

All-NRTI Regimens

...

Dolutegravir, Abacavir, and Lamivudine

...

Pediatric Patients

...

All-NRTI Regimens

...

PI-based Regimens

...

Once-daily versus Twice-daily Regimens

...

Postexposure Prophylaxis following Occupational Exposure to HIV

...

Postexposure Prophylaxis following Nonoccupational Exposure to HIV

...

...

Dosage and Administration

Dosage and Administration

...

Administration

...

Fixed Combinations Containing Abacavir

...

Dosage

...

Adult Dosage

...

Treatment of HIV Infection

...

Postexposure Prophylaxis following Occupational Exposure to HIV

...

Pediatric Dosage

...

Treatment of HIV Infection

...

Table 1. Twice-daily Regimen in Children and Adolescents Weighing ≥14 kg Able to Swallow Tablets (Ziagen® 300-mg Tablets)1

...

Table 2. Once-daily Regimen in Children and Adolescents Weighing ≥14 kg Able to Swallow Tablets (Ziagen® 300-mg Tablets)1

...

Dosage in Renal and Hepatic Impairment

...

Renal Impairment

...

Hepatic Impairment

...

...

Cautions

Cautions

...

Hypersensitivity Reactions

...

Hepatic Effects and Lactic Acidosis

...

GI Effects

...

Cardiovascular Effects

...

Adipogenic Effects

...

Immune Reconstitution Syndrome

...

Other Adverse Effects

...

Precautions and Contraindications

...

Precautions Related to Hypersensitivity Reactions

...

Precautions Related to Use of Fixed Combinations

...

Other Precautions

...

Pediatric Precautions

...

Geriatric Precautions

...

Mutagenicity and Carcinogenicity

...

Pregnancy, Fertility, and Lactation

...

Pregnancy

...

Fertility

...

Lactation

...

...

Drug Interactions

Drug Interactions

...

Drugs Affecting Hepatic Microsomal Enzymes

...

Alcohol

...

Antiretroviral Agents

...

HIV Entry and Fusion Inhibitors

...

HIV Integrase Inhibitors (INSTIs)

...

Elvitegravir

...

HIV Nonnucleoside Reverse Transcriptase Inhibitors (NNRTIs)

...

HIV Nucleoside and Nucleotide Reverse Transcriptase Inhibitors (NRTIs)

...

Lamivudine and Zidovudine

...

Tenofovir

...

HIV Protease Inhibitors (PIs)

...

Darunavir

...

Fosamprenavir

...

Lopinavir

...

Tipranavir

...

HCV Antivirals

...

HCV Protease Inhibitors

...

Simeprevir

...

HCV Replication Complex Inhibitors

...

Elbasvir and Grazoprevir

...

Ledipasvir and Sofosbuvir

...

Opiates and Opiate Partial Agonists

...

Methadone

...

Ribavirin

...

...

Acute Toxicity

Acute Toxicity

...

Manifestation

...

Treatment

...

...

Pharmacokinetics

Pharmacokinetics

...

Absorption

...

Food

...

Distribution

...

Elimination

...

...

Chemistry and Stability

Chemistry and Stability

...

Chemistry

...

Stability

...

...

Spectrum Section

Spectrum

...

Retroviruses

...

Other Viruses

...

...

Resistance Section

Resistance

...

Cross-resistance

...

...

Mechanism of Action

Mechanism of Action

...

Antiviral Effects

...

Cytotoxic Effects

...

...

Preparations

Preparations

...

Abacavir Sulfate

...

Abacavir Sulfate Combinations

...

...

References

References

...

...

Copyright

AHFS® Drug Information. © Copyright, 1959-2020, Selected Revisions May 1, 2017. American Society of Health-System Pharmacists, Inc., 4500 East-West Highway, Suite 900, Bethesda, Maryland 20814.

† Use is not currently included in the labeling approved by the US Food and Drug Administration.

Quelle

AHFS Drug Information