Monograph: Enfortumab Vedotin-ejfv

Enfortumab Vedotin-ejfv

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Full Title

Enfortumab Vedotin-ejfv

Generic Name

Enfortumab Vedotin

Chemical Name

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INV Number

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Classification

CAS Number

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Introduction

Introduction

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Description

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Uses

Uses

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Urothelial Carcinoma

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Dosage and Administration

Dosage and Administration

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General

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Restricted Distribution

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Administration

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Reconstitution and Dilution

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Dosage

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Urothelial Carcinoma

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Dosage Modification for Toxicity

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Table 1: Recommended Dosage Reduction for Enfortumab Vedotin Toxicity1

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Table 2. Recommended Dosage Modification for Enfortumab Vedotin Toxicity1

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Special Populations

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Hepatic Impairment

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Renal Impairment

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Cautions

Cautions

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Contraindications

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Warnings/Precautions

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Hyperglycemia

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Peripheral Neuropathy

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Ocular Effects

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Dermatologic Effects

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Extravasation

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Fetal/Neonatal Morbidity and Mortality

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Immunogenicity

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Infertility

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Specific Populations

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Pregnancy

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Lactation

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Pediatric Use

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Geriatric Use

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Hepatic Impairment

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Renal Impairment

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Common Adverse Effects

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Drug Interactions

Drug Interactions

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Drugs Affecting Hepatic Microsomal Enzymes

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CYP3A4 Inhibitors

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CYP3A4 Inducers

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Drugs Metabolized by Hepatic Microsomal Enzymes

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Advice to Patients

Advice to Patients

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Preparations

Preparations

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Enfortumab Vedotin-ejfv

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Common general statement Elements

Additional Information

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References

References

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Copyright

AHFS® Drug Information. © Copyright, 1959-2020, Selected Revisions October 19, 2020. American Society of Health-System Pharmacists, Inc., 4500 East-West Highway, Suite 900, Bethesda, Maryland 20814.

Quelle

AHFS Drug Information