Monograph: Casirivimab and Imdevimab
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Casirivimab and Imdevimab
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Full Title
Casirivimab and Imdevimab
Generic Name
Casirivimab; Imdevimab
INV Number
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Synonym
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Classification
Introduction
Introduction
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...Description
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Spectrum
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Resistance
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...Uses
Uses
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Coronavirus Disease 2019 (COVID-19)
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Emergency Use Authorization (EUA)
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Outpatients with Mild to Moderate COVID-19
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Patients Hospitalized with COVID-19
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...Dosage and Administration
Dosage and Administration
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General
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Administration
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Dosage and Administration Precautions
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IV Infusion
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Table 1. Instructions for Combining and Diluting Casirivimab and Imdevimab in 0.9% Sodium Chloride for IV Infusion1
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Rate of Administration
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Dosage
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Adult Dosage
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Coronavirus Disease 2019 (COVID-19)
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Pediatric Dosage
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Coronavirus Disease 2019 (COVID-19)
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Special Populations
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Hepatic Impairment
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Renal Impairment
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...Cautions
Cautions
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Contraindications
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Warnings/Precautions
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Sensitivity and Infusion-related Reactions
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Limitations of Benefit and Potential for Risk in Patients with Severe COVID-19
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EUA Requirements for Patient Monitoring and Mandatory FDA MedWatch Reporting
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Specific Populations
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Pregnancy
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Lactation
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Pediatric Use
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Geriatric Use
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Hepatic Impairment
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Renal Impairment
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Common Adverse Effects
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...Drug Interactions
Drug Interactions
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...Pharmacokinetics
Pharmacokinetics
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Absorption
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Distribution
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Elimination
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Special Populations
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...Stability Section
Stability
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Solution Concentrates for Injection, for IV Infusion
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...Advice to Patients
Advice to Patients
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...Preparations
Preparations
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Casirivimab
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Imdevimab
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...Common general statement Elements
Additional Information
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...References
References
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...Copyright
AHFS® Drug Information. © Copyright, 1959-2020, Selected Revisions December 3, 2020. American Society of Health-System Pharmacists, Inc., 4500 East-West Highway, Suite 900, Bethesda, Maryland 20814.
† Use is not currently included in the labeling approved by the US Food and Drug Administration.
Quelle
AHFS Drug Information
