Monograph: Indomethacin

Indomethacin

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Full Title

Indomethacin

Generic Name

Indomethacin; Indomethacin Sodium Trihydrate

Synonym

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Classification

CAS Number

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Introduction

Introduction

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Uses

Uses

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Inflammatory Diseases

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Rheumatoid Arthritis and Osteoarthritis

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Gout

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Ankylosing Spondylitis

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Pericarditis

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Other Inflammatory Conditions

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Patent Ductus Arteriosus

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Genitourinary and Renal Diseases

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Fever

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Orthostatic Hypotension

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Pulmonary Hypertension

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Cystoid Macular Edema

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Other Uses

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Dosage and Administration

Dosage and Administration

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Reconstitution and Administration

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Oral and Rectal Administration

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IV Administration

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Dosage

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Inflammatory Diseases

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Rheumatoid Arthritis, Osteoarthritis, and Ankylosing Spondylitis

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Acute Exacerbations of Chronic Rheumatoid Arthritis

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Gout

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Acute Painful Shoulder

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Juvenile Arthritis

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Pericarditis

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Patent Ductus Arteriosus

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Genitourinary and Renal Diseases

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Cautions

Cautions

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Cardiovascular Effects

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GI Effects

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Nervous System Effects

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Hematologic Effects

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Ocular and Otic Effects

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Renal and Electrolyte Effects

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Dermatologic and Sensitivity Reactions

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Hepatic Effects

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Respiratory Effects

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Other Adverse Effects

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Precautions and Contraindications

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Pediatric Precautions

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Geriatric Precautions

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Pregnancy, Fertility, and Lactation

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Pregnancy

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Fertility

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Lactation

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Drug Interactions

Drug Interactions

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Protein-bound Drugs

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Anticoagulants and Thrombolytic Agents

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Alcohol

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Nonsteroidal Anti-inflammatory Agents

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Hypotensive Agents and Diuretics

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Digoxin

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Drugs Increasing Serum Potassium Concentrations

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Lithium

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Methotrexate

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Cyclosporine

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Probenecid

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Other Drugs

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Acute Toxicity

Acute Toxicity

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Pathogenesis

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Manifestation

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Treatment

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Pharmacology

Pharmacology

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Anti-inflammatory, Analgesic, and Antipyretic Effects

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Genitourinary and Renal Effects

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Cardiovascular Effects

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Hematologic Effects

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GI Effects

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Metabolic Effects

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Pharmacokinetics

Pharmacokinetics

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Absorption

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Distribution

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Elimination

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Chemistry and Stability

Chemistry and Stability

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Chemistry

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Stability

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Laboratory Test Interference

Laboratory Test Interferences

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Preparations

Preparations

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Indomethacin

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Indomethacin Sodium

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References

References

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Copyright

AHFS® Drug Information. © Copyright, 1959-2020, Selected Revisions November 9, 2020. American Society of Health-System Pharmacists, Inc., 4500 East-West Highway, Suite 900, Bethesda, Maryland 20814.

† Use is not currently included in the labeling approved by the US Food and Drug Administration.

Quelle

AHFS Drug Information