Monograph: COVID-19 Vaccine, mRNA (Moderna)

COVID-19 Vaccine, mRNA (Moderna)

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Full Title

COVID-19 Vaccine, mRNA (Moderna)

Generic Name

COVID-19 Vaccine, mRNA (Moderna)

Synonym

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Classification

Introduction

Introduction

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Description

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Uses

Uses

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Prevention of Coronavirus Disease 2019 (COVID-19)

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Emergency Use Authorization

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Clinical Experience

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Adults

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Immunocompromised Individuals

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Dosage and Administration

Dosage and Administration

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General

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Administration

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IM Injection

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Thawing

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Dosage

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Adult Dosage

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Immunocompromised Adults

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Cautions

Cautions

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Contraindications

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Warnings/Precautions

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Sensitivity Reactions

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Hypersensitivity Reactions

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Lymphadenopathy

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Myocarditis and Pericarditis

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Thrombocytopenia

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Concomitant Illness

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Individuals with Current SARS-CoV-2 Infection

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Individuals with Recent Exposure to SARS-CoV-2 Infection

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Individuals with Prior SARS-CoV-2 Infection

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Individuals with a History of Multisystem Inflammatory Syndrome

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Individuals with Underlying Medical Conditions

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Individuals with Altered Immunocompetence

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Individuals with Autoimmune Conditions

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Individuals with Liver Disease

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Individuals with a History of Guillain-Barré Syndrome

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Individuals with a History of Bell's Palsy

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Individuals with Increased Bleeding Risk

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History of Dermal Filler Use

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Individuals Vaccinated Outside the US

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Fully or Partially Vaccinated with an FDA-authorized COVID-19 Vaccine

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Previously Received a COVID-19 Vaccine not Authorized by FDA but Listed for Emergency Use by WHO

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Previously Received a COVID-19 Vaccine not Authorized by FDA or Listed for Emergency Use by WHO

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Limitations of Vaccine Effectiveness

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Duration of Immunity

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Improper Storage and Handling

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EUA Requirements for Postvaccination Monitoring and Mandatory Vaccine Adverse Event Reporting

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Interpretation of SARS-CoV-2 Testing in Vaccinated Individuals

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Interpretation of Tuberculosis Tests in Vaccinated Individuals

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Specific Populations

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Pregnancy

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Females and Males of Reproductive Capacity

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Lactation

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Pediatric Use

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Geriatric Use

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Common Adverse Effects

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Drug Interactions

Drug Interactions

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Antiviral Agents

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Immune Globulins and Antibody Therapies

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SARS-CoV-2 Antibody Therapies

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Immunosuppressive Agents

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Vaccines

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Stability Section

Stability

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Suspension, for IM Use

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Advice to Patients

Advice to Patients

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Preparations

Preparations

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COVID-19 Vaccine, mRNA (Moderna)

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Common general statement Elements

Additional Information

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References

References

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Copyright

AHFS® Drug Information. © Copyright, 1959-2021, Selected Revisions August 25, 2021. American Society of Health-System Pharmacists, Inc., 4500 East-West Highway, Suite 900, Bethesda, Maryland 20814.

† Use is not currently included in the labeling approved by the US Food and Drug Administration.

Quelle

AHFS Drug Information