Monograph: Atorvastatin Calcium

Atorvastatin Calcium

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Full Title

Atorvastatin Calcium

Generic Name

Atorvastatin Calcium

INV Number

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Classification

CAS Number

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Introduction

Introduction

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Description

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Uses

Uses

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Prevention of Cardiovascular Events

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Primary Prevention

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Patients without Clinical Evidence of CHD

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Patients with Diabetes Mellitus

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Secondary Prevention

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Patients with Clinical Evidence of CHD

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High-intensity Statin Therapy

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Reducing Progression of Coronary Atherosclerosis

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Intensity of Statin Therapy

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Combination Antilipemic Therapy

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Patients with Chronic Kidney Disease

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Dyslipidemias

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Primary Hypercholesterolemia or Mixed Dyslipidemia

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Adults

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Pediatric Patients

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Hypertriglyceridemia

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Primary Dysbetalipoproteinemia

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Homozygous Familial Hypercholesterolemia

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Other Uses

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Dosage and Administration

Dosage and Administration

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General

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Administration

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Dosage

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Prevention of Cardiovascular Events

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Primary Prevention

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Secondary Prevention

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Dyslipidemias

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Primary Hypercholesterolemia (Heterozygous Familial and Nonfamilial) or Mixed Dyslipidemia

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Homozygous Familial Hypercholesterolemia

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Atorvastatin/Amlodipine Combination Therapy

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Concomitant Drug Therapy

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Dosage Modification

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Special Populations

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Cautions

Cautions

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Contraindications

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Warnings/Precautions

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Fetal/Neonatal Morbidity and Mortality

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Musculoskeletal Effects

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Hepatic Effects

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Endocrine Effects

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Cognitive Impairment

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Use in Patients with Recent Stroke or Transient Ischemic Attack

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Use of Fixed Combination

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Specific Populations

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Pregnancy

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Lactation

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Pediatric Use

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Geriatric Use

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Hepatic Impairment

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Renal Impairment

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Common Adverse Effects

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Drug Interactions

Drug Interactions

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Drugs and Foods Affecting Hepatic Microsomal Enzymes

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Drugs Transported by Organic Anion Transport Polypeptide 1B1

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Azole Antifungals

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Bile Acid Sequestrants

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Colchicine

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Cyclosporine

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Digoxin

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Efavirenz

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Fibric Acid Derivatives

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Grapefruit Juice

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HIV Protease Inhibitors

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Darunavir

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Fosamprenavir

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Lopinavir

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Nelfinavir

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Saquinavir

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Tipranavir

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Lomitapide

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Macrolide Antibiotics

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Niacin

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Omega-3-acid Ethyl Esters

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Oral Contraceptives

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Rifampin

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Warfarin

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Advice to Patients

Advice to Patients

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Preparations

Preparations

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Atorvastatin Calcium

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Atorvastatin Calcium Combinations

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Common general statement Elements

Additional Information

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References

References

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Copyright

AHFS® Drug Information. © Copyright, 1959-2020, Selected Revisions June 26, 2017. American Society of Health-System Pharmacists, Inc., 4500 East-West Highway, Suite 900, Bethesda, Maryland 20814.

† Use is not currently included in the labeling approved by the US Food and Drug Administration.

Quelle

AHFS Drug Information