Oliceridine Fumarate

Full Title

Oliceridine Fumarate

Generic Name

Oliceridine

Chemical Name

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Classification

Introduction

Introduction

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Uses

Uses

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Oliceridine fumarate has the following uses:

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Oliceridine fumarate has the following limitations of use:

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Dosage and Administration

Dosage and Administration

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General

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Injection:

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Dosage

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Adults

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Dosage and Administration

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Cautions

Cautions

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Contraindications

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Warnings/Precautions

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Addiction, Abuse, and Misuse

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Life-threatening Respiratory Depression

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Neonatal Opioid Withdrawal Syndrome

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Risks from Concomitant Use with Benzodiazepines or Other CNS Depressants

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Potential for QT Prolongation with Daily Doses Exceeding 27 mg

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Risk of Use in Patients with Decreased Cytochrome P-450 2D6 Function or Concomitant Use or Discontinuation with Cytochrome P-450 3A4 Inhibitors and Inducers

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Risk of Increased Oliceridine Plasma Concentrations

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Risk of Lower than Expected Oliceridine Plasma Concentrations

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Life-threatening Respiratory Depression in Patients with Chronic Pulmonary Disease or in Elderly, Cachectic, or Debilitated Patients

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Patients with Chronic Pulmonary Disease

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Elderly, Cachectic, or Debilitated Patients

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Adrenal Insufficiency

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Severe Hypotension

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Risks of Use in Patients with Increased Intracranial Pressure, Brain Tumors, Head Injury, or Impaired Consciousness

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Risks of Use in Patients with Gastrointestinal Conditions

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Increased Risk of Seizures in Patients with Seizure Disorders

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Withdrawal

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Risks of Driving and Operating Machinery

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Patient-controlled Analgesia (PCA)

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Specific Populations

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Pregnancy

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Lactation

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Females And Males Of Reproductive Potential

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Pediatric Use

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Geriatric Use

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Renal Impairment

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Hepatic Impairment

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Poor Metabolizers of CYP2D6 Substrates

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Common Adverse Effects

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Drug Interactions

Drug Interactions

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Specific Drugs

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Mechanism of Action

Actions

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Mechanism of Action

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Advice to Patients

Advice to Patients

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Serotonin Syndrome

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Constipation

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Preparations

Preparations

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Oliceridine Fumarate

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Common general statement Elements

Additional Information

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References

References

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Copyright

AHFS® Drug Information. © Copyright, 1959-2021, Selected Revisions December 14, 2020. American Society of Health-System Pharmacists, Inc., 4500 East-West Highway, Suite 900, Bethesda, Maryland 20814.

Quelle

AHFS Drug Information
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  2. https://www.drugbase.de/en/databases/ahfs/classification.html?tx_crondavdbahfs_pi%5Bcategory%5D=206&cHash=628df160d08cca251d6607c6159d471d
  3. https://www.drugbase.de/en/databases/ahfs/classification.html?tx_crondavdbahfs_pi%5Bcategory%5D=211&cHash=5471a01d572da5a33fbf1324cb020295